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glutathione respiratory burst Immunology burst Cell surface proteins Glutathione (GSH) is the most important nonprotein thiol widely distributed in animal tissues Role of Glutathione in Neutrophil Figure 24.12 from Oxygen Toxicity and Free Radical Injury Semantic Scholar Switching to the cyclic pentose phosphate pathway powers the oxidative burst in activated neutrophils Nature Metabolism 1 The ascorbate glutathione (AsA GSH) cycle is often regarded as the Download Scientific Diagram Phagocytic immune cells, including macrophages and neutrophils, play a central role in the innate immune response by rapidly generating reactive oxygen species (ROS) through the NADPH oxidase 2 (NOX2) enzyme complex. This
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