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Although the functional correlation between optically measurable parameters such as size and intensity of gephyrin clusters and inhibitory synapse function is currently unknown, EM studies have shown that increased synaptic strength in inhibitory synapses produces a coordinated insertion of GABA A Rs and enlargement of the PSD (Nusser et al., 1998)

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Nos estudos animais, as doses eficazes situam-se entre 10 g/kg e 10 ng/kg (via oral ou subcutnea)

Insomnia and depressive behavior of MyD88-deficient mice: relationships with altered microglial functions