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Side effects and safety of the combination The side-effect profile of the combination is essentially the union of the individual profiles, with no documented additive concerns at typical clinical doses

Certain underlying health conditions may also prevent your body from properly absorbing vitamin B

Metabolization of vitamins varies widely amongst populations, as faster metabolizers clear the bloodstream quicker, necessitating shorter intervals for maintaining a consistent supply compared to their slower counterparts

However, any combination approach should be undertaken with medical supervision and careful monitoring of cumulative effects

Varying intervals of maintenance doses will then follow it