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In whole-cell voltage clamp experiments, excitatory postsynaptic currents (EPSCs) were measured at the membrane potential of 70 mV for 3 min

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elegans and Homo sapiens are able to translocate ER proteins for lysosomal eradication via macroautophagy via GRP78-IRE1 mediation of the UPRER and further recruitment of translocon Sec-62 (in worms, an orthologous C18E19.2) (Fumagalli et al., 2016

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Minor injection site pain within 18 hours but then arm started to pull up at elbow and sharp nerve pain in wrist began on extension of arm