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For example, RuBisCO unfolds, disrupting its secondary and tertiary structure, with a complete loss of enzymatic activity at temperatures over 65 C 66

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At a 10% concentration, cell viability remained above 80% for all types tested

Cancer Res 79:17491750 Gan W, Dai X, Dai X, Xie J, Yin S, Zhu J, Wang C, Liu Y, Guo J, Wang M et al (2020) LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control

Applications in plant biotechnology: Focus on plant secondary metabolism and plant molecular pharming (CRC Press, 2022A)