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This process and its linkage with cytosolic GSL synthesis requires two transport steps across the chloroplast envelope, as the first reaction allowing Met to enter biosynthesis of GSLs is a deamination of Met by a cytosolic BCAT4 ( Figure 2 , transporter 8)

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Effective delivery of Piezo1 inhibitors to tumor regions in the brain and ensuring drug stability and efficacy remain challenges to be addressed in clinical translational research