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doi: 10.1146/annurev-arplant-042811-105439

Quantitative analysis of the compound present in assay buffer sampled from the apical and the basolateral compartments which are separated by the cell monolayer enables determination of apparent permeability coefficient, P app of the compound

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Key Research Characteristics: Selective NNMT inhibition, supporting studies into NAD metabolism and methylation pathways Investigated in the context of obesity, metabolic dysfunction, and lipid accumulation models Cell-permeable small molecule with favourable in vitro profile Studied for potential effects on adipocyte differentiation and energy expenditure Specifications: Form: Lyophilised powder For research purposes only