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Animal Model:Timed-pregnant Long Evans rats [4] Dosage:350 mg/kg Administration:Intraperitoneal injection, once Result:Demonstrated more social investigation and play fighting than control animals

10.1016/j.immuni.2019.06.025 [DOI] [PMC free article] [PubMed] [Google Scholar] 94.Qin X, Gu Y, Liu T, Wang C, Zhong W, Wang B, et al

Soliman Wadan AH, Abdelsattar Ahmed M, Hussein Ahmed A, El-Sayed Ellakwa D, Hamed Elmoghazy N, Gawish A

For example, upon CT infection, IFN production induces the activation of the enzyme IDO1 which depletes the tryptophan pool within the epithelial cells into kynurenine

Patients with mitochondrial diseases, which can result from mutations in either mitochondrial chromosome encoded genes or nuclear genes that encode mitochondrial proteins, typically manifest with neuromuscular symptoms