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However, in patients with BD, neuropsychological performance is closely related to cortisol [160], and higher levels of this hormone have been related to poorer performance in some cognitive tasks [161, 162], especially working memory [163]

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Somatostatin analog: plasma catecholamine suppression mediated by the central nervous system

More visible whitening and even skin tone results typically appear within 4 to 6 weeks, while best results are achieved after 6 to 8 weeks of regular use