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METHODS SUBJECTS The Framingham Heart Study is a longitudinal population-based study in which subjects have been examined every 2 years.15 The dementia study began at examination cycles 14 to 15, when participants underwent a neuropsychological test battery (age range, 55-88 years).1 At the 20th biennial examination (1986-1988), 1921 subjects from this cohort were alive and free of dementia

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Since absorption of vitamin B12 depends on a protein called intrinsic factor produced in your stomach, some individuals may find it difficult to absorb the vitamin efficiently

Gastroenterology 125, 696707 (2003)