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Vitamin B 12 deficiency is a common cause of megaloblastic anemia, various neuropsychiatric symptoms, and other clinical manifestations

Drug-Drug Interactions Optineuron Injection may interact with the following medicines: Antiparkinson medicines such as levodopa: Pyridoxine may reduce the effectiveness of levodopa when used without a dopa decarboxylase inhibitor, potentially worsening Parkinsons disease symptoms

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Verhoef et al, 1994) and some prospective nested case-controlled studies (Arnesen et al, 1995