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In some cases, patients with certain medical histories or conditions may need to consider alternative therapies or modify their treatment approach

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Overexpression of ATF3 suppresses the differentiation of M1 (pro-inflammatory) macrophage, as evidenced by the decreased expression of M1 markers such as TNF- and CD11c in adipose tissues, thereby attenuating local inflammation (179)

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These findings suggest that the interaction between condensin and the general transcription factor TBP contributes to condensin loading to gene loci 16