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doi: 10.1016/j.biocel.2013.01.018 27 LerchK

Some researchers have proposed that the pathological mechanisms of PD may originate in the gut, with -Syn pathology spreading to the brain in a bottom-up manner (39)

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A Spider Toxin Exemplifies the Promises and Pitfalls of Cell-Free Protein Production for Venom Biodiscovery

198 In the study conducted by Peek et al., it was similarly observed that knockdown of Bmal1 ( ACTA-rtTA-TRE-Cre, Bmal fx/fx ) in mouse skeletal muscle resulted in a reduction in HIF-1 accumulation and decreased sensitivity to the simulated hypoxic environment