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The spatial navigation impairments in young Tg4-42 mice are well in line with the hypometabolism and synaptic deficits in the hippocampus

Upon entry of testosterone into the androgen target cell, binding occurs to the androgen receptor either directly or after its conversion to 5-dihydrotestosterone

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In the United States, nearly 90,000 new cases are identified annually, and the number has grown by 50% in recent years possibly due to advancements in diagnostic techniques 34

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