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Huntington's disease Huntington's disease (HD) is a chronic neurodegenerative disease and a hereditary autosomal-dominant disorder of the central nervous system caused by a single genetic mutation (Ross et al., ), characterized by neuronal death in caudate and putamen and in the cerebral cortex, and to a lesser extent in hippocampus and subthalamic nucleus (Mehrotra et al., )

Our data show that ablation of this response via knockdown leads to devastating outcomes

Future studies should extend the age range or utilize meta-analysis to integrate multiple studies to investigate how brain GSH levels vary over the lifespan

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