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The observed risk is highest in males 12 through 17 years of age

Dillon et al., in a phase I clinical trial, evaluated a vaccine containing nine breast-cancer-associated peptides (MHC I restricted) from MAGE-A1, 3A3, and AA10 proteins, CEA, NY-ESO-1, and HER2/neu along with a TLR3 agonist, Poly-ICLC, and an adjuvant derived from tetanus toxin

Thomson, Down-regulation of argininosuccinate synthetase is associated with cisplatin resistance in hepatocellular carcinoma cell lines: Implications for PEGylated arginine deiminase combination therapy