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Moreover, we found that for both CD4 and CD8 CAR T cells, HK and G6PD expression levels showed a significant correlation, further supporting the potentially coupled activity of the two step-limiting rate enzymes of glycolysis and the PPP, respectively (Fig

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Statistics and reproducibility Descriptive statistics included proportions for categorical variables and using medians and interquartile ranges (IQRs) for continuous variables

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Proteome datasets were further filtered to improve the robustness of the downstream analysis by removing proteins that were not quantified in at least two biological replicates in at least one condition

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