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doi: 10.1080/07853890.2023.2215542 8 HanSChenMChengPZhangZLuYXuYet al

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One of its main components salvianolic acid A acts as an antioxidant by reducing Ang-II-induced NADPH oxidase-4 (Nox4), which decreases reactive oxygen species and, as a result, suppresses Src and Akt activation

Lipid oxidation, through excess ROS (increased oxidative stress), marked by decreased GPx may occur in both patients with arrhythmias and dyslipidemia, which will result in endothelial damage with early initiation of atherosclerosis (14-17)