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Toxicology 376:214

Intriguingly, Metro generated a well-defined specificity pocket at the active site that is absent in HpTx red as well as in YpTpx ox (Supplementary Fig

The peptide was subsequently described as a cytoprotectant with the radical property of being stable in gastric juice and therefore accessible for both gastric and intestinal protection after oral administration

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OTA was found to chelate ferric ions (Fe 3 ), facilitating their reduction to ferrous ions (Fe 2 ), which in the presence of oxygen, provided the active species initiating LPO [74]