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Furthermore, the lag period before telomere shortening occurs following TERT inhibition is problematic for aggressively proliferating tumors such as GBMs (4,6,7)

However, treatment should not be delayed whilst awaiting test results if clinical suspicion is high, particularly when neurological symptoms are present

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Vilela et al., 2020), and boosting the expression of neurogenesis-related and proliferative genes in aged animals (He et al., 2017) and enhanced aquaporin 4 expression and localization to astrocytic end feet

Statins for Graves' orbitopathy (STAGO): a phase 2, open-label, adaptive, single centre, randomised clinical trial