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Nano-curcumin prevents cardiac injury, oxidative stress and inflammation, and modulates TLR4/NF-B and MAPK signaling in copper sulfate-intoxicated rats

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[112] investigated whether there was a correlation between C677T polymorphism, birth weight, and the risk of developing CVD in 113 morbidly obese French adolescents (BMI = 39.1 6.4 kg/m 2 ) at the age of 14.4 1.5 years

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Since tumor cells with certain oncogenic mutations are very sensitive to ferroptosis, triggering ferroptosis may also have significant therapeutic potential for ferroptosis-sensitive tumor cells ( c /GSH/GPX4 axis have been shown to be fatal in host cells

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Parkin then ubiquitinates outer mitochondrial membrane proteins, recruiting autophagy receptors like OPTN and NDP52, ultimately leading to the engulfment and degradation of damaged mitochondria by autophagosomes (Zhang C

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This results in joint pain, deformity, and disability (Yoo et al., 2009)

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