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When levels are managed correctly, side effects are minimal

Both peptides are commonly prescribed together because they stimulate growth hormone release through different pathways -- sermorelin through GHRH receptor activation and ipamorelin through ghrelin receptor activation

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[1] It has also been studied, in NIH-funded research, for HIV-associated fatty liver disease (NAFLD/MASLD), and earlier in its development program it was investigated for indications as varied as wasting, sleep, and mild cognitive impairment most of which did not advance