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Figure 1) (Panche et al., 2016)

However, mutational analysis demonstrated that androgen driven upregulation of IGF-1R was not driven by AR genomic activity but involved the activation of the Src-extracellular signal-regulated kinase pathway (Pandini et al., 2005)

Where does this data come from

The production of inflammatory cytokines such as TNF-, IL-1, IL-6, IL-12, IL-15, IL-17, and IL-23 contribute to exacerbate the inflammatory response in the CNS (Jensen et al., 2013)