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Wright RA

The role of increased autophagic activity in the pathology of cancer, neurodegeneration, cardiovascular disease and diabetes has become widely recognized and commonly studied

But, in an animal that is not eating, there is a lack of available protein to do this, so fat builds up in the liver and disrupts liver function

Micutkova et al., 2011), further mitigating the chronic inflammation that drives fibrosis

J Nutr 130:1007S1015S Melzer N, Hicking G, Bittner S, Bobak N, Gobel K, Herrmann AM, Wiendl H, Meuth SG (2013) Excitotoxic neuronal cell death during an oligodendrocyte-directed CD8 + T cell attack in the CNS gray matter