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Enzymatic Response Profiling: Analysing activation and inhibition behaviour across molecular pathways

In the Zucker fatty rat, which is hyperinsulinaemic but has normal blood glucose, the activities of PC, MDH and ME are increased to support the pyruvate cycling activity required to increase GSIS during this metabolic overload [37]

77 Mice that overexpress ECSOD or NOX-deficient mice are each protected against oxidative damage and lung inflammation associated with cigarette smoke

The reads were mapped to the reference sequence using a short read aligner based on Burrows-Wheeler transform (Tophat v2-2.1) with default settings

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