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Glutathione Metabolism and Its Implications for Health. The Journal of Nutrition

Factors responsible for the liver's contribution to drug metabolism include that it is a large organ, that it is the first organ perfused by chemicals absorbed in the gut, and that there are very high concentrations of most drug-metabolizing enzyme systems relative to other organs

Their comparative analysis demonstrated the advantages of PRIT over RIT

A second abnormality is a lack of sensory-motor integration, which is related to mild sensory complaints in patients with focal dystonias and may be responsible for some of the motor dysfunction