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Clinical research published in Biochemical Pharmacology demonstrates that 5 amino 1mq treatment significantly reduces NNMT activity in adipocytes, leading to increased intracellular NAD+ concentrations

It plays an indispensable role in the production of neurotransmitters and the maintenance of healthy nerve cells

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Moreover, experimental studies employing RNA interference (RNAi) strategies and small molecule inhibitors targeting NNMT have underscored its potential as a therapeutic target for preventing or treating MetS-related diseases