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Of note, over-activation of the HGF/MET pathway through germline MET and sporadic MET mutations or even protein over-expression increases tumorigenesis and tumor progressions in numerous cancer forms, such as renal cell carcinoma, metaplasia-dysplasia-adenocarcinoma evolution in esophageal cancer, osteosarcomas, and melanomas, as well as brain, gastric, gliomas, breast, and head and neck cancers [1, 4,5,6]

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Preclinical studies have provided encouraging evidence of Dihexas potential in improving stroke recovery

It has been reported that morin can reduce astrocyte activation, inhibit inflammatory responses, and subsequently prevent the degeneration of DAn in an MPTP-induced mouse model of PD (Lee et al., 2016)

Cell culture and treatment FL83B mouse hepatocytes (ATCC , Manassas, VA) were cultured and maintained in F-12K complete medium