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Among the six primary flavonoids analyzed for their antibacterial properties including isoorientin, vitexin, isovitexin, rutin, quercetin, and kaempferol quercetin emerged as the most effective, demonstrating robust antibacterial activity against all the tested bacteria except for E

Peptide-based therapeutics have emerged as a promising class of agents due to their high target specificity, structural versatility, and ability to modulate proteinprotein interactions central to AD pathogenesis

We are grateful to members of the Hit Discovery and Structural Design team: Roxanne Smith and Daniel Hinchen for supporting the XChem fragment screens, and Marc Cabry for sharing his expertise in XChem data analysis

J Exp Med 203:28412852

Inhibition of myeloid-derived suppressive cell function with all-trans retinoic acid enhanced anti-PD-L1 efficacy in cervical cancer