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The primary antibodies were rabbit anti-FGF5 antibody (Thermo Fisher Scientific, USA), goat anti-SRD5A1 antibody (Abcam, UK), rabbit anti-androgen receptor antibody (Abcam, UK), goat anti-DKK1 antibody (Abcam, UK), beta-catenin polyclonal antibody (Proteintech, USA), c-MYC polyclonal antibody (Proteintech, USA), and beta tubulin monoclonal antibody (Proteintech, USA)

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1 According to the WHO, in 2019, antibiotic resistance caused an estimated 1.27 million deaths directly and contributed to nearly 5 million deaths worldwide

46 Because middle-aged women, aged 4065 years, have the highest risk of developing fibromyalgia, hormone fluctuations that occur in the menopause transition have been proposed as a possible trigger