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However, it was regarded as the third gaseous signal molecule after carbon oxide (CO) and nitric oxide (NO) recently ( 2 S production, namely, cystathionine gamma-lyase (CSE), 3-mercaptopyruvate sulfurtransferase (3-MST), and cystathionine-beta-synthase (CBS) ( 2 S production, CBS catalyzes the -substitution reaction of homocysteine with serine to generate cystathionine

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