l-glutathione complex gsh gold Glutathione: Pharmacological aspects and implications for clinical use in non-alcoholic fatty liver disease Glutaryl: Antioxidant Glutathione Spray |

miR-142-5p, and miR-34a (Koval et al., 2013

In light of this data, FGF21 stands out as an important hepatokine for both diagnostic and therapeutic purposes in MASLD, particularly for early diagnosis, monitoring disease progression, and targeting treatment [237]

Redox homeostasis is controlled by a variety of cell defense mechanisms, including three different superoxide dismutase (SOD1 in cells, SOD2 in mitochondria, SOD3), glutathione peroxidase (GPX), and signal pathways Nuclear factor erythroid 2-related factor 2 (NRF2)- Kelch-like ECH-associated protein 1(KEAP1) (71)

Distinct microRNA populations control white adipocyte differentiation and brown/beige adipocyte thermogenic programming (289, 290)

Figure 1 Redox Dysregulation Oxidative stress results from elevated intracellular levels of ROS, and nitrosative stress results from increased levels of RNS, and both events can significantly damage cells