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Despite the growing understanding of the associations between ECD and many cardiac diseases, there is an increasing need for relevant models of ECD and EC-CM signaling that better interrogate the key disruptions that drive ECD and CMD into an overt cardiac phenotype

In studies of animals with induced glaucoma, researchers found that placing melatonin in the anterior chamber of the eye reversed the negative effect of ocular hypertension on retinal function and diminished the impact of ocular hypertension on retinal ganglion cells

Therefore, the nutrient is not only a key nutrient for growth and development, but a vital component of a healthy pregnancy

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doi: 10.1016/j.cca.2006.03.011