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Description

Consistently, the livers of HFD-fed mice showed increased IKK--SSG levels, decreased IKK- phosphorylation, and suppressed NF-B activation when compared to these from control animals

liver Dis

Together, these data demonstrate that metformin treatment in combination with radiation induces significant alterations to cell cycle progression, with differing effects on the radiosensitive HCT116 and radioresistant SW837 cell lines