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Surprisingly, we demonstrate here that, in an acute setting, mice with combined liver-specific deletion of Gclc and Nrf2 do not lose weight or show poor health or liver failure

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403 The CpG motif is prevalent in bacteria, and the CpG motif also recognizes plasmacytoid dendritic cells (pDC) expressing TLR9 that produce pro-inflammatory cytokines, induce Th1-like immune activation patterns and activate their migration, while CpG-A oligodeoxynucleotides (ODN) induces extremely high levels of IFN- production and CpG-B ODN induces activation of murine bone marrow-derived DCs to secrete IL-12 and IL-6

doi: 10.1128/IAI.66.11.5379-5387.1998 [DOI] [PMC free article] [PubMed] [Google Scholar] [68].Hanson MS, Cassatt DR, Guo BP, et al