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In a phase 2 trial, setmelanotide was dosed at 1 mg/24 h SC infusion over 90 days (NCT01749137) (87)

Malaguarnera and colleagues randomized 74 patients with NASH to receive either L-Carnitine (a 1 gram tablet after breakfast and another after dinner) or placebo for 24 weeks

Exclusion of competing etiology: A careful history and work up for exclusion of competing etiology is crucial as DILI is primarily a diagnosis of exclusion

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[2] Treatment Treatment is targeted at suppressing the inflammatory response and preventing cardiac involvement