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Senzolo, M

Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver

However, the addition of exogenous GSH reduced activities of the PA synthesis-enzymes like arginine decarboxylase (ADC), S-adenosylmethionine decarboxylase (SAMDC), and diamine oxidase (DAO), while increased the activities of polyamine oxidase (PAO) and ornithine decarboxylase (ODC), resulting in reduced levels of PAs such as Spd, Spm and Put