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However, the timing of discontinuation matters because of the long half-life

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Certain medications particularly insulin secretagogues or other glucose-lowering agents may need dose adjustments when combined with semaglutide due to its glycemic effects

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In addition, ROS generation by phagocytes, like macrophages and neutrophils, is also the cause of NP-induced oxidative stress (Horie and Tabei, 2021)

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