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If there is no -minimal joint change evident on XRay with high pain levels, an MRI may be indicated to rule out insufficiency fracture, and check for early indicators of rapidly progressive hip OA (joint effusion, synovitis, adjacent soft-tissue changes, subchondral bone marrow oedema)

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1Aoutlines the major elements of the mammalian NAD+ salvage pathway using NA as the starting substrate

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