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Interestingly, like oxaliplatin (this study), MMC can also be detoxified by glutahthione [44], suggesting that the combination treatment strategy identified in the present study may be beneficial for both oxaliplatin- and MMC-based HIPEC

This research sought to assess the possible impact of the SOX4/EZH2 axis on ferroptosis in the pathogenesis of CaOx-induced kidney injury and evaluate the protective effect of EZH2 inhibition