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A significant advantage of NPs is their ability to avoid bacterial resistance by exerting toxic effects on via DNA degradation, and lipid and protein peroxidation (155, 156)

and accounting for the influence of sample size, particle size, and digestion time

In another study from the same laboratory, Babar et al., developed silymarin loaded nanostructured lipid carrier for the treatment of skin cancer

Berberine (BBR) An isoquinoline alkaloid derived from plants such as Berberis species, berberine improves glucose and lipid metabolism by suppressing hepatic lipid synthesis, reducing inflammation, modulating gut microbiota, and attenuating oxidative stress

This flexible approach is tailored on the need of each patient, and the most used regimen is between 240 mg and 480 mg of DMF per day