acetaminophen napqi glutathione alcohol - MSK Acetaminophen metabolism and NAPQI-mediated mitochondrial

Acetaminophen metabolism and NAPQI mediated mitochondrial effects Download Scientific Diagram What happens when you take paracetamol? Your liver gets to work breaking it down into harmless bits. But here's the twist Those bits need a taxi (yep, a molecule called glutathione) The Metabolism of Acetaminophen and the Synthesis of Glutathione Download Scientific Diagram Acetaminophen (Paracetamol) Toxicity A common and potentially fatal cause of acute liver failure due to toxic accumulation of the metabolite NAPQI when glutathione stores are depleted. Early recognition and timely administration Metabolic pathway for NAPQI formation and detoxification by conjugation Download Scientific Diagram

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