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PMID: 28254787

Measurement of the inhibition zones revealed that ethanol-containing extracts exerted more substantial antimicrobial effects than those obtained with other solvents (354)

However, this significance was not observed in the meta-analysis of the two randomized controlled trials (RCTs) conducted exclusively in vivo

Watermelon is considered a high FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) fruit, which means it contains short-chain sugars that some people have trouble digesting, Derocha says, so it may cause bloating or discomfort when consumed in large amounts. People with diabetes or who may need to count their carbohydrate servings should also pay attention to their watermelon intake, she adds

Legal Classification IGF-1 LR3 and DES : Not classified as controlled substances, but not approved for medical use Sale for human consumption : Illegal under FDA regulations Possession : Legal for research purposes, but not for ingestion or injection in humans The FDA has not evaluated IGF-1 peptides for safety or effectiveness in humans