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A review on BPC 157 was published in Current Reviews in Musculoskeletal Medicine in August 2025, acknowledging the potential benefits and unknown long term risks but noted that no adverse effects have been reported to date in available studies

This exact scenario accounts for a large portion of the adverse events the FDA has documented

10.1007/978-3-030-16073-9_3 Nutrition and Immunity 52

However, it appears that this compound does not subsequently accumulate in the lung tissue, which is a phenomenon that warrants further investigation

A conserved role for the protein phosphatase 2A (PP2A)-associated protein 4 in the sensing of glutamine has been reported