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also showed that elesclomol transports divalent copper to mitochondria, where it is reduced to the more toxic monovalent copper, promoting a mitochondrial ROS response that leads to apoptosis (129)

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10.1016/j.toxlet.2021.03.006 127 LiH.ShiL.ChenX.WangM

Contraindicated in pregnancy, breastfeeding and known hypersensitivity to glutathione or any component

Successful remyelination comprises several highly orchestrated events including migration, proliferation, terminal differentiation of OPC, and myelination (Stangel and Hartung, 2002)

Oxalate induces type II epithelial to mesenchymal transition (EMT) in inner medullary collecting duct cells (IMCD) in vitro and stimulate the expression of osteogenic and fibrotic markers in kidney medulla in vivo