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By improving insulin sensitivity and reducing overall insulin demand, GLP-1 RAs address one of the primary drivers of the condition not just a symptom

however, in meta-analysis these factors did not reach statistical significance

Nerve injuries: In sciatic nerve transection models, early axonal sprouting is detectable histologically within the first 714 days (Gjurasin et al., 2010)

A much smaller percentage of people deficient in B12 have pernicious anemia which occurs more frequently in those over 60 accounting for 1-2% of all deficiencies

BALANCE (Better Approaches to Lifestyle and Nutrition for Comprehensive hEalth) Model opens in new window , CMS.gov, last accessed April 24, 2026