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As in C6/36 Wp , all four anti- Wolbachia drugs significantly induced autophagy in C6/36 cells, as expressed by both autophagy markers (Figure 4)

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Here, we used human studies and in vitro models to demonstrate that NAPQI-derived thiomethyl metabolites identified using high-resolution mass spectrometry could serve to monitor NAPQI detoxification and elimination in patients (after intake at recommended dose or after intoxication), and to study inter-individual variability in NAPQI production

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