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Description

Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks

However, they mutually inhibit each other, ultimately determining the final fate of the cell

The mitochondria-targeted drug Met attenuates upregulation of the immune checkpoints programmed cell death protein 1 (PD-1) and lymphocyte activation gene-3 (LAG-3), thereby increasing CD8 + T cell infiltration and survival in the harsh tumor microenvironment (271)