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Description

Despite multimodal treatment strategies, including surgical resection, radiotherapy, and temozolomide (TMZ) chemotherapy, recurrence is inevitable due to glioma stem cells (GSCs) and therapy-induced resistance mechanisms [1]

As a result, the temporal profiled of H 2 O 2 secreted from the cells cultured in different formats can be characterized in a straightforward manner without tedious medium filtration or purification processes ( In the experiments, human hepatocellular carcinoma cell line is cultured, and H 2 O 2 secretin of the cells in two formats: single cell and three-dimensional (3D) spheroid are characterized