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During the propagative phase, molecular oxygen reacts with phospholipid radicals rapidly, leading to the formation of phospholipid peroxy radicals (PLOO)

Structures of mitochondrial oxidative phosphorylation supercomplexes and mechanisms for their stabilisation

Hence, lean individuals with metabolic diseases should also be screened for MASLD [63]

Additional stability testing at room temperature and under accelerated conditions, along with formal pharmacokinetic profiling in biological media, is recommended

When the TSA method was used, the sections were treated with biotinylated goat anti-mouse/rabbit IgG (1:1000 dilution, Vector Laboratories, Burlingame, CA) for 1 h, and then incubated with HRP-conjugated-avidin for 30 min (1:100 dilution in TN buffer, TSA System) at room temperature